New Method Offers Deeper Look at Gene Regulation in Cells

Scientists have unveiled RENGE, a powerful tool for untangling the complex web of gene interactions within cells. RENGE analyzes time-series data after CRISPR gene editing, providing a more complete picture than traditional methods. This allows it to distinguish direct from indirect gene regulation, even revealing how unedited genes influence the network.

RENGE captures the cascading effects of gene knockouts, offering a sharper view. This accuracy can pinpoint key players in biological systems, opening the door to future discoveries.

Initial tests on stem cells produced a network aligned with known science, highlighting RENGE’s potential. By deciphering the intricate language of genes, RENGE could lead to new therapies.

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