Columbia University researchers conducted a comprehensive study on mice, revealing that repeated ketamine use over ten days induces notable alterations in the brain’s dopamine system. The findings emphasize the necessity of targeted ketamine treatments to minimize unintended effects on dopamine regions. While this study provides unprecedented detail on the brain’s response to ketamine, its implications for human application remain speculative. The research suggests potential connections to eating disorders and hints at the importance of specific brain region targeting in mitigating adverse effects. This ground-breaking brain mapping approach offers valuable insights into ketamine’s nuanced impact at the cellular level.
Source: https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01503-6