U.S.-Iranian relations lurched downward as the political sanctions imposed by Trump administration restricts the scientific progress and researches in Iran. Iranian scholars have been denied opportunities to publish scientific findings, attend meetings, access essential medical and laboratory supplies and information. It has prompted many high impact journals and publishers to refuse to handle research papers from Iran. The punitive sanctions are limiting the researchers’ freedom as well as the nation’s ability to progress in terms of scientific advancements. Moreover, the economic and health impacts of sanction have been far-reaching, extending to the greater Middle East region, undermining research and publications as well.